IFs, however, are different to microfilaments and microtubules in a number of fundamental respects. First, they tend to be more or less permanent structures in tissues such as skin and hair; in fact, in these non-living tissues IF proteins are almost the only protein. (Therefore, it is true, if somewhat prosaic, to say that beauty is only IF thick). In other cell types, IFs are modified by phosphorylation when they are required to be disassembled for example during cell division. Unlike the highly conserved actins and tubulins, more than 40 distinct IF proteins are encoded by a number of genes in mammalian cells. All IF proteins have a similar structure with a central helical rod domain and more variable head and tail domains.
The IFs can be divided into five major classes as follows:
Related category• CELL BIOLOGY
Home • About • Copyright © The Worlds of David Darling • Encyclopedia of Alternative Energy • Contact