Markarian's Chain is a spectacular arc of galaxies in the central region of the Virgo
Cluster. The Chain starts with the two bright elliptical
galaxies M84 (NGC 4374, at R.A. 12h 25m, Dec. +12° 53' and M86 (NGC
4406) and curves away to the northeast, taking in NGC 4435, NGC 4438, NGC
4458, NGC 4461, NGC 4473, and NGC 4477. There is no compelling evidence
that any of the systems in the Chain are interacting.