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A carcinoma is any of the various types of malignant tumors that form in the epithelial tissue, the tissue forming the outer layer of the body surface and lining the digestive tract and other hollow structures. A carcinoma is thus distinguished from a sarcoma, which arises in bone, muscle, or connective tissue. Carcinomas include all the most common cancers including skin, breast, lung, and prostate cancer.

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Source: National Human Genome Research Institute