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    leprosy

    Also known as Hansen's disease, a chronic disease caused by a myobacterium and virtually restricted to tropical zones. Leprosy leads to skin nodules with loss of pigmentation, mucous membrane lesions in nose and pharynx, and neuritis with nerve thickening, loss of pain sensation, and patchy weakness, often involving ace and intrinsic hand muscles. Diagnosis is by demonstrating the organisms in stained scrapings or by skin or nerve biopsy. The type of disease caused depends on the number of bacteria encountered and basic resistance to the disease. Treatment is with sulfones (Dapsone).


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