cholecystokinin
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Cholecystokinin molecule.
Source: PubChem
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Previously known as pancreozymin, a peptide hormone
of the gastrointestinal system responsible for stimulating the digestion
of fat and protein. Cholecystokinin (CCK) is secreted by the duodenum
(the first part of the small intestine) and causes the release of digestive
enzymes from the pancreas and bile
from the gall bladder. It also acts
as a hunger suppresant. Recent evidence has suggested that it plays a major
role in inducing drug tolerance to opioids like morphine and heroin, and
is partly responsible for the pain hypersensitivity often experienced during
opioid withdrawal.
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