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Grignard reagent




Any of a family of organometalic compounds of great importance in laboratory and industrial chemical synthesis. Grignard reagents are made by reacting alkyl halides or aryl halides with magnesium in an ether solution, and are commonly represented as RMgX, where R is an alkyl group or aryl group. They are powerful nucleophiles, and react with many compounds, introducing the group R. Examples are methylmagnesium iodide (CH3MgI) and phenylmagnesium bromide (C6H5MgBr). The Grignard reagents are named after the French chemist François Grignard (1871–1935) who discovered them in 1900.


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   • ORGANIC CHEMISTRY