Causes of beriberiThere are two major types of beriberi:
A rare condition known as genetic beriberi is inherited (passed down through families). People with genetic beriberi lose the ability to absorb thiamine from foods. This can happen slowly over time and symptoms occur when the person is an adult. However, because doctors may not consider beriberi in non-alcoholics, this diagnosis is often missed.
Beriberi can occur in breast-fed infants when the mother's body is lacking in thiamine. The condition can also affect infants who are fed unusual formulas that don't have enough thiamine.
Getting dialysis and taking high doses of diuretics increase the your risk of beriberi.
Symptoms of beriberiSymptoms of dry beriberi include:
Exams and tests for beriberiA physical examination may show signs of congestive heart failure, including:
A neurological exam may show signs of:
TreatmentThe goal of treatment is to replace the thiamine your body is lacking. This is done with thiamine supplements. Thiamine supplements are given through a shot (injection) or taken by mouth. Other types of vitamins may also be recommended.
Blood tests may be done after you are given thiamine supplements to see how well you are responding to the medicine.
PrognosisUntreated, beriberi is often deadly. With treatment, symptoms usually improve quickly.
Heart damage is usually reversible, and a full recovery is expected. However, if acute heart failure has already occurred, the outlook is poor.
Nervous system damage is also reversible, if caught early. If it is not caught early, some symptoms (such as memory loss) may remain even with treatment.
If a patient with Wernicke's encephalopathy receives thiamine replacement, language problems, unusual eye movements, and walking difficulties may go away. However, Korsakoff syndrome (or Korsakoff psychosis) tends to develop as Wernicke's symptoms go away.
Related category HEALTH AND DISEASE
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