CELL BIOLOGY
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    mitochondria

    diagram of a mitochondrion
    Mobile, self-replicating organelles that occur in various numbers, shapes, and sizes in the cytoplasm of all eukaryotic cells. Mitochondria contain their own genome that is separate and distinct from the nuclear genome of a cell.

    Mitochondria have two functionally distinct membrane systems separated by a space: the outer membrane, which surrounds the whole organelle; and the inner membrane, which is thrown into folds or shelves that project inward. These inward folds are called cristae. The number and shape of cristae in mitochondria differ, depending on the tissue and organism in which they are found, and serve to increase the surface area of the membrane.

    photo of a mitochondrion
    Mitochondrian. Photo credit: D. S. Friend, Brigham and Women's Hospital
    Mitochondria are the site of the citric acid cycle, also known as the Kreb's cycle, which is a vital metablic pathway for generating energy in eukaryotic cells.

    The origin of mitochondria is explained by the endosymbiotic theory.


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       • CELL BIOLOGY



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