Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary gland.
PathologyDopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, since dopamine cannot cross the blood-brain barrier, if given as a drug it does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and dopa-responsive dystonia, L-dopa (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier.
Dopamine levels are influenced by the use of certain psychoactive drugs such as nicotine, cocaine, amphetamines, and ecstasy.
Related category• BIOCHEMISTRY
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